Sugar Sugar Rune

Sugar Sugar Rune (シュガシュガルーン, Shuga Shuga Rūn?) or Sugar² Rune is a manga by Moyoco Anno and an anime TV series based upon it. The anime series' time slot was replaced by Demashita! Powerpuff Girls Z in mid-2006.

Plot
The story is about two best friends, Chocolat Meilleure and Vanilla Mieux, who are young witches from the Magical World.

Other Sources

 * Sugar Sugar Rune
 * http://www.animenewsnetwork.com/encyclopedia/anime.php?id=5334