The Tale of the Outcasts

Nokemono-tachi no Yoru (ノケモノたちの夜) is a manga series by Makoto Hoshino. It is serialized in Weekly Shōnen Sunday. It has been licensed in English as The Tale of the Outcasts by Seven Seas Entertainment.

Plot
Wisteria is an orphan girl living in a corner of the British Empire at the end of the 19th century. Her life is desolate and bleak–until she encounters Malbus, a powerful but equally lonely immortal being with a furry appearance, hounded by hunters. Together, Wisteria and Malbus roam the Empire–populated by humans and human-like beasts–in search of a place where they can live together in peace.