Sugar Sugar Rune

or Sugar² Rune is a manga by Moyoco Anno and an anime TV series based upon it.

Plot
The story is about two best friends, Chocolat Meilleure and Vanilla Mieux, who are young witches from the Magical World.

Other Sources

 * Sugar Sugar Rune
 * http://www.animenewsnetwork.com/encyclopedia/anime.php?id=5334