DNA²

is a Japanese science fiction manga series written and illustrated by Masakazu Katsura. It was serialized across Shueisha's Weekly Shōnen Jump magazine between 1993 and 1994, spanning a total of five tankōbon volumes.

It was adapted into a 12-episode anime television series which ran on Nippon Television from October 7, 1994 to December 23, 1994. This was followed by a three-episode anime original video animation (OVA) in 1995. All 15 episodes were licensed in North America by Central Park Media until their closing in 2009. The five volumes and box set are out-of-print until Discotek Media re-licensed the series for a DVD release in 2014.

Plot
Karin, a DNA operator from the future, is on a mission to change the course of History by stopping Junta Momonari from becoming the Mega-Playboy who fathered 100 children and led to the overpopulation of the world. But Junta is no playboy; in fact he is allergic to girls. But when Karin shoots him with the wrong DNA-altering bullet, he starts sporadically becoming the Mega-Playboy capable of charming any woman. Karin must try to restore the situation to normal before the change to Mega-Playboy becomes irreversible.