Ghost in the Shell

is a franchise that started out as a manga created by Shiro Masamune. It mostly follows an organization called Section 9 that works to stop terrorists. One of the main characters, and what most plots in this franchise follow, is Motoko Kusanagi.

It's set in a futuristic (cyberpunk/post cyberpunk) world where prosthetic bodies are the norm.

Ghost in the Shell has two two anime series, three manga series, two anime T.V. series, two films, three OVAs, two games, and four novels.