Most well written protagonist and antagonist in your opinion..
Try to mention top 2-3
1 Naruto - Pain
2 Gon - Hisoka
3 Edward - The homunculus
Goku, Naruto and Luffy are my forever favourite protagonists if all time.
For antagonists, I really liked Sasuke and Vegeta when they were still antagonists.
Not to mention, One Piece and Hunter X Hunter have some of the absolute best antagonists.
What do you think?