Danchigai (だんちがい, lit. "Big Difference") is a four-panel comedy manga series by Kazusa Yoneda, serialized in Ichijinsha's seinen manga magazine Manga 4-Koma Palette since June 2011. The series has received an anime television series adaptation, which began airing in July 2015.
The story revolves around Haruki and his four sisters: Mutsuki, Yayoi, Uzuki, and Satsuki. While their life may seem monotonous aside from the fact that Haruki's sisters don't give him a single opportunity to rest, lecturing him about every perceived mistake and playing tricks on him but Haruki still loves his life.
Anime official website (Japanese)