Years before the start of No Bra, Masato Kataoka and Yuki Nomura were childhood friends, though they were later separated—with Masato soon forgetting anything about the friendship and Yuki still treasuring those memories. Masato grows to become a high school student enrolled in Meikyuu Private Academy, whereas Yuki moves from school to school, never quite fitting in because of his crossdressing and feminine appearance. One day, Yuki moves in with Masato and starts going to school with him. Yuki promptly becomes one of the most popular "girls" in the class, alongside Kaoru Oozora, whom Masato nurses a crush on. Meanwhile, Yuki continues to refuse all of Masato's pleas for him to act more manly, forcing Masato to stop any idea that Yuki and Masato live together, while also juggling his feelings for Yuki and Kaoru.